Immune deficiency augments the prevalence of p53 loss of heterozygosity in spontaneous tumors but not bi-directional loss of heterozygosity in bone marrow progenitors
نویسندگان
چکیده
منابع مشابه
Loss of heterozygosity and p53 gene mutations in breast cancer.
Immunopositivity for the p53 tumor suppressor gene product was evaluated in 133 breast cancers and compared to loss of heterozygosity (LOH) at various chromosomal loci. The validity of p53 immunopositivity as an indicator for p53 mutations was verified using two molecular assays of p53 mutations: single stranded conformational polymorphism (32 cases) and/or direct sequencing (14 cases). Immunop...
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15 صفحه اولSpontaneous loss of heterozygosity in diploid Saccharomyces cerevisiae cells.
To obtain a broad perspective of the events leading to spontaneous loss of heterozygosity (LOH), we have characterized the genetic alterations that functionally inactivated the URA3 marker hemizygously or heterozygously situated either on chromosome III or chromosome V in diploid Saccharomyces cerevisiae cells. Analysis of chromosome structure in a large number of LOH clones by pulsed-field gel...
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this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
the effect of taftan pozzolan on the compressive strength of concrete in the environmental conditions of oman sea (chabahar port)
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2017
ISSN: 0020-7136
DOI: 10.1002/ijc.30554